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Rationale and Evidence for EZH1/2 Inhibitors in PTCL

Clinical Thought
Read this commentary for expert insights on the management of PTCL and emerging clinical trial evidence with EZH1/2 inhibitors in different PTCL subtypes.

Released: August 08, 2022

Expiration: August 07, 2023

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Faculty

Pamela B. Allen

Pamela B. Allen, MD, MSc

Assistant Professor
Department of Hematology/Oncology
Emory University, Winship Cancer Institute
The Emory Clinic
Atlanta, Georgia

Steven M. Horwitz

Steven M. Horwitz, MD

Assistant Attending Physician, Lymphoma Service
Department of Medicine
Memorial Sloan-Kettering Cancer Center
New York, New York

Pierluigi Porcu

Pierluigi Porcu, MD

Professor and Director
Division of Hematology Malignancies
Department of Medical Oncology
Thomas Jefferson University
Philadelphia, Pennsylvania

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Supporters

Supported by an educational grant from

Daiichi Sankyo, Inc.

Program Director Disclosure

Program Director

Steven M. Horwitz, MD

Assistant Attending Physician, Lymphoma Service
Department of Medicine
Memorial Sloan-Kettering Cancer Center
New York, New York

Steven M. Horwitz, MD: consultant/advisor/speaker: Acrotech, Affimed, Cimeio Therapeutics, Daiichi Sankyo, Kura Oncology, Kyowa Hakko Kirin, Myeloid Therapeutics, ONO Pharmaceuticals, Secura Bio, Shoreline Biosciences, Takeda, Trillium, Tubulis, Vividion Therapeutics, Yingli Pharma; researcher: ADC Therapeutics, Affimed, C4 Therapeutics, Celgene, Crispr Therapeutics, Daiichi Sankyo, Kyowa Hakko Kirin, Millennium/Takeda, Seattle Genetics, Verastem/Secura Bio.

Faculty Disclosure

Primary Author

Pamela B. Allen, MD, MSc

Assistant Professor
Department of Hematology/Oncology
Emory University, Winship Cancer Institute
The Emory Clinic
Atlanta, Georgia

Pamela B. Allen, MD: advisor: Daiichi Sankyo.

Pierluigi Porcu, MD

Professor and Director
Division of Hematology Malignancies
Department of Medical Oncology
Thomas Jefferson University
Philadelphia, Pennsylvania

Pierluigi Porcu, MD: consultant/advisor/speaker: Daiichi Sankyo, Dren Bio, Innate Pharma, Loxo Oncology, MorphoSys, Viracta.