Faculty

Sanjay J. Mathew, MD

Professor and Vice Chair for Research
Baylor College of Medicine
Houston, Texas

Jonathan M Meyer, MD, DLFAPA

Voluntary Clinical Professor of Psychiatry
University of California, San Diego
Senior Academic Advisor
California Department of State Hospitals
San Diego, California

Provided by

Provided by Clinical Care Options, LLC

Supporters

Supported by an educational grant from Sage Therapeutics, Inc. and Biogen.

Sage Therapeutics, Inc. and Biogen

Target Audience

This program is intended for healthcare professionals caring for patients with major depressive disorder, including psychiatrists, primary care physicians, nurse practitioners, physician associates/physician assistants, registered nurses, pharmacists, social workers, and psychologists.

Learning Objectives

Upon completion of this activity, participants should be able to:

Describe the role of glutamate and GABA in the pathophysiology of MDD
Identify medications that modulate glutamate or GABA for the treatment of MDD
Assess the efficacy and safety of new and emerging medications that modulate glutamate or GABA for MDD

Disclosure

Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Sanjay J. Mathew, MD: consultant/advisor/speaker: Almatica, Clexio, Neumora, Perception Neurosciences, Relmada, Sage, Sunovion; researcher: Boehringer Ingelheim, Neurocrine.

Jonathan M. Meyer, MD: consultant/advisor/speaker: Alkermes, Axsome, Cervel, Intra-Cellular Therapies, Karuna, Neurocrine, Noven, Otsuka America, Relmada, Sunovion Pharmaceuticals, Teva Pharmaceuticals.

The planners and content peer reviewers from Clinical Care Options, LLC do not have any relevant financial relationships to disclose, except Gabrielle Giacona and Michael Asbach, DMSc, PA-C, Psych-CAQ, as noted below.

Gabrielle Giacona: individual publicly traded stock/stock options: AstraZeneca, Moderna.
Michael Asbach, DMSc, PA-C, Psych-CAQ: consultant/advisor/speaker: AbbVie, Avanir, Biogen, Janssen, Karuna, Neurocrine, Otsuka.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 1 hours. To successfully complete this activity and receive credit, learners must follow these steps during the period from June 22, 2023, through June 21, 2024:

Login or Sign Up for an account by clicking at the top of this page
Read the target audience, learning objectives, and faculty disclosures
View and study the content in its entirety
Submit answers to the post-test questions and evaluation questions online

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.

Format

This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Accreditation

Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

CCO designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 1 contact hour, including 1 hour of pharmacology credit.

Continuing Pharmacy Education

CCO designates this continuing education activity for 1 contact hour (0.1 CEUs) of the Accreditation Council for Pharmacy Education.
Universal Activity Number - JA4008176-0000-23-176-H01-P

Type of Activity: Application

Upon successfully completing the post-test with a score of 65 and the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.

Physician Assistant/Physician Associate Continuing Medical Education

Clinical Care Options, LLC has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1 AAPA Category 1 CME credit. Approval is valid until June 21, 2024. PAs should only claim commensurate with the extent of their participation.

Social Work Continuing Education

As a Jointly Accredited Organization, Clinical Care Options, LLC is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. Social workers completing this course receive 1 clinical continuing education credit.

Psychologist Continuing Education

Continuing education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs.

This activity offers 1 continuing education credit for psychologists.

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Modulators of Glutamate and GABA for MDD

Video