MDD Treatment: Augment or Switch
Expert Advice on MDD Treatment: When to Augment or Switch

Physicians: Maximum of 0.25 AMA PRA Category 1 Credit

Released: January 01, 2025

Expiration: April 16, 2025

References

2019-2020 Florida Best Practice Psychotherapeutic Medication Guidelines for Adults, Agency for Health Care Administration, State of Florida, 2020.

Gelenberg AJ, Freeman MP, Markowitz JC, et al. Practice guideline for the treatment of patients with major depressive disorder. Available at: https://psychiatryonline.org/pb/assets/raw/sitewide/practice_guidelines/guidelines/mdd.pdf. Accessed March 24, 2020.

McIntyre RS, Fallu A, Konarski JZ. Measurable outcomes in psychiatric disorders: remission as a marker of wellness. Clin Ther. 2006;28:1882-1891.

Schueller SM, Kwasny MJ, Dear BF, et al. Cut points on the Patient Health Questionnaire (PHQ-9) that predict response to cognitive-behavioral treatments for depression. Gen Hosp Psychiatry. 2015;37:470-475.

Zimmerman M, Posternak MA, Chelminski I. Derivation of a definition of remission on the Montgomery-Asberg depression rating scale corresponding to the definition of remission on the Hamilton rating scale for depression. J Psychiatr Res. 2004;38:577-582.

Disclaimer: Access to and use of this Interactive Decision Support Tool titled, “Expert Advice on MDD Treatment: When to Augment or Switch is provided subject to the following terms and conditions. PLEASE READ THESE TERMS CAREFULLY.

This Interactive Decision Support Tool is designed to educate clinicians on making optimal management choices when advancing treatment for MDD. The information provided is based on expert guidance of Leslie Citrome, MD, MPH; Christoph U. Correll, MD; Rakesh Jain, MD, MPH; Roger McIntyre, MD, FRCPC; and Michael E. Thase, MD.

The material published by Clinical Care Options reflects the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the accredited provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Although the information contained in the “Expert Advice on MDD Treatment: When to Augment or Switch” Interactive Decision Support Tool has been produced and processed from sources believed to be reliable, no warranty, expressed or implied, is made regarding the accuracy, adequacy, completeness, legality, reliability, or usefulness of any information. This disclaimer applies to both the isolated and aggregate uses of the information. Clinical Care Options provides this information on an as-is basis. This disclaimer applies to all material published by Clinical Care Options including but not limited to medical information or opinions. All warranties of any kind, expressed or implied, including but not limited to the implied warranties of merchantability, fitness for a particular purpose, freedom from contamination by computer viruses, and noninfringement of proprietary rights are disclaimed.

Any trademarks are the property of respective companies.
© 2020 Clinical Care Options, LLC. All rights reserved.

Program Content